Tennessee vs. Mississippi State odds, line: 2025 college basketball picks, January 21 best bets by proven model

No. 6 Tennessee Volunteers will host No. 14 Mississippi State Bulldogs on Tuesday night in SEC play, and the conference continues to look like the deepest in the nation. After winning their first 14 games, the Volunteers have lost two of four and are now 16-2 overall and 3-2 in the SEC. Meanwhile, the Bulldogs are 15-3 on the season, 3-2 in the league and should be emboldened after winning by 17 points in Knoxville as 9.5 point underdogs last year.

Tipoff from Thompson-Boling Arena in Knoxville, Tenn., is set for 6 p.m. 19 A.M. The Volunteers are an 8.5 point favorite in the latest Tennessee vs. Mississippi State odds from the SportsLine consensus, while the over/under for total points scored is 142.5.

Before entering the Mississippi State vs. Tennessee pick, you’ll want to see NCAA Basketball predictions from the model at SportsLine.

The model simulates each Division 1 college basketball game 10,000 times. It goes into Week 12 of the 2024-25 season at one 198-138 roll (+2692) on all top-rated college basketball picks going back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Tennessee vs. Mississippi State 10,000 times and the results are in. We can tell you that the model leans over and it also says that one side of the spread hits almost 60% of the time!

So who will win Mississippi State vs. Tennessee and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread to jump on, all from the computer model who has crushed his college basketball picks!